Domain
State of the field
Plausible prebiotic chemistries exist for many building blocks, but no demonstrated continuous path from geochemistry to a living cell, and the order of events is debated.
A spark discharge through a reducing gas mixture produced amino acids, showing biologically relevant molecules can form from simple precursors under plausible e…
Powner et al. synthesized activated pyrimidine ribonucleotides via a route bypassing free ribose and base, a major boost to the plausibility of an RNA-world ori…